Yersiniabactin-Producing Adherent/Invasive Escherichia coli Promotes Inflammation-Associated Fibrosis in Gnotobiotic Il10(−/−) Mice

Fibrosis is a significant complication of intestinal disorders associated with microbial dysbiosis and pathobiont expansion, notably Crohn’s disease (CD). Mechanisms that favor fibrosis are not well understood, and therapeutic strategies are limited. Here we demonstrate that colitis-susceptible Il10...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Ellermann, Melissa, Gharaibeh, Raad Z., Fulbright, Laura, Dogan, Belgin, Moore, Lyndsey N., Broberg, Christopher A., Lopez, Lacey R., Rothemich, Aaron M., Herzog, Jeremy W., Rogala, Allison, Gordon, Ilyssa O., Rieder, Florian, Brouwer, Cory R., Simpson, Kenneth W., Jobin, Christian, Sartor, R. Balfour, Arthur, Janelle C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803345/
https://ncbi.nlm.nih.gov/pubmed/31481410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00587-19
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