Yersiniabactin-Producing Adherent/Invasive Escherichia coli Promotes Inflammation-Associated Fibrosis in Gnotobiotic Il10(−/−) Mice

Fibrosis is a significant complication of intestinal disorders associated with microbial dysbiosis and pathobiont expansion, notably Crohn’s disease (CD). Mechanisms that favor fibrosis are not well understood, and therapeutic strategies are limited. Here we demonstrate that colitis-susceptible Il10...

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Udgivet i:Infect Immun
Main Authors: Ellermann, Melissa, Gharaibeh, Raad Z., Fulbright, Laura, Dogan, Belgin, Moore, Lyndsey N., Broberg, Christopher A., Lopez, Lacey R., Rothemich, Aaron M., Herzog, Jeremy W., Rogala, Allison, Gordon, Ilyssa O., Rieder, Florian, Brouwer, Cory R., Simpson, Kenneth W., Jobin, Christian, Sartor, R. Balfour, Arthur, Janelle C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Host Response and Inflammation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803345/
https://ncbi.nlm.nih.gov/pubmed/31481410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00587-19
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