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Functional investigation of the BRCA1 Val1714Gly and Asp1733Gly variants by computational tools and yeast transcription activation assay
Mutations in the BRCA1 gene are known to be a major cause of hereditary breast cancer. However, characterizing the point mutations associated with cancer in BRCA1 is challenging because the functional impact of most of them is still unknown. Nowadays, a variety of methods are employed to identify ca...
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| Vydáno v: | Mol Biol Res Commun |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Shiraz University
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6802689/ https://ncbi.nlm.nih.gov/pubmed/31998812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22099/mbrc.2019.33971.1414 |
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