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In silico analysis for determining the deleterious nonsynonymous single nucleotide polymorphisms of BRCA genes

Recent advances in DNA sequencing techniques have led to an increase in the identification of single nucleotide polymorphisms (SNPs) in BRCA1 and BRCA2 genes, but no further information regarding the deleterious probability of many of them is available (Variants of Unknown Significance/VUS). As a re...

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Detalhes bibliográficos
Publicado no:Mol Biol Res Commun
Main Authors: Yadegari, Fatemeh, Majidzadeh, Keivan
Formato: Artigo
Idioma:Inglês
Publicado em: Shiraz University 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6995337/
https://ncbi.nlm.nih.gov/pubmed/32042831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22099/mbrc.2019.34198.1420
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