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In silico analysis for determining the deleterious nonsynonymous single nucleotide polymorphisms of BRCA genes

Recent advances in DNA sequencing techniques have led to an increase in the identification of single nucleotide polymorphisms (SNPs) in BRCA1 and BRCA2 genes, but no further information regarding the deleterious probability of many of them is available (Variants of Unknown Significance/VUS). As a re...

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Bibliografiske detaljer
Udgivet i:Mol Biol Res Commun
Main Authors: Yadegari, Fatemeh, Majidzadeh, Keivan
Format: Artigo
Sprog:Inglês
Udgivet: Shiraz University 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6995337/
https://ncbi.nlm.nih.gov/pubmed/32042831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22099/mbrc.2019.34198.1420
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