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In silico analysis for determining the deleterious nonsynonymous single nucleotide polymorphisms of BRCA genes

Recent advances in DNA sequencing techniques have led to an increase in the identification of single nucleotide polymorphisms (SNPs) in BRCA1 and BRCA2 genes, but no further information regarding the deleterious probability of many of them is available (Variants of Unknown Significance/VUS). As a re...

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Publicado en:Mol Biol Res Commun
Autores principales: Yadegari, Fatemeh, Majidzadeh, Keivan
Formato: Artigo
Lenguaje:Inglês
Publicado: Shiraz University 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6995337/
https://ncbi.nlm.nih.gov/pubmed/32042831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22099/mbrc.2019.34198.1420
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