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An In Silico Evaluation of Deleterious Nonsynonymous Single Nucleotide Polymorphisms in the ErbB3 Oncogene

ErbB3 is a significant oncogenic target that is involved in the development of numerous malignancies. In the present in silico study, we evaluated the structural and functional impact of single nucleotide polymorphisms (SNPs) on the ErbB3 gene. The nonsynonymous SNPs (nsSNPs) are known to be deleter...

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Bibliographische Detailangaben
Hauptverfasser: Raghav, Dhwani, Sharma, Vinay
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666215/
https://ncbi.nlm.nih.gov/pubmed/23741632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/biores.2013.0007
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