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An In Silico Evaluation of Deleterious Nonsynonymous Single Nucleotide Polymorphisms in the ErbB3 Oncogene

ErbB3 is a significant oncogenic target that is involved in the development of numerous malignancies. In the present in silico study, we evaluated the structural and functional impact of single nucleotide polymorphisms (SNPs) on the ErbB3 gene. The nonsynonymous SNPs (nsSNPs) are known to be deleter...

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Detalhes bibliográficos
Main Authors: Raghav, Dhwani, Sharma, Vinay
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666215/
https://ncbi.nlm.nih.gov/pubmed/23741632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/biores.2013.0007
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