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Functional investigation of the BRCA1 Val1714Gly and Asp1733Gly variants by computational tools and yeast transcription activation assay

Mutations in the BRCA1 gene are known to be a major cause of hereditary breast cancer. However, characterizing the point mutations associated with cancer in BRCA1 is challenging because the functional impact of most of them is still unknown. Nowadays, a variety of methods are employed to identify ca...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Mol Biol Res Commun
Asıl Yazarlar: Yadegari, Fatemeh, Farahmand, Leila, Esmaeili, Rezvan, Samadi, Tannaz, Majidzadeh, Keivan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Shiraz University 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6802689/
https://ncbi.nlm.nih.gov/pubmed/31998812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22099/mbrc.2019.33971.1414
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