High levels of Daxx due to low cellular levels of HSP25 in murine cancer cells result in inefficient adenovirus replication

When the adenoviral protein E1B55K binds death domain-associated protein (Daxx), the proteasome-dependent degradation of Daxx is initiated, and adenoviral replication is effectively maintained. Here, we show that the cellular levels of Daxx differ between human and mouse cancer cell lines. Specifica...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Exp Mol Med
Prif Awduron: Han, Zhezhu, Joo, Yeonsoo, Lee, Jihyun, Ko, Suwan, Xu, Rong, Oh, Geun-Hyeok, Choi, Soojin, Hong, Jeong A., Choi, Hye Jin, Song, Jae J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6802665/
https://ncbi.nlm.nih.gov/pubmed/31615977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-019-0321-4
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