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High levels of Daxx due to low cellular levels of HSP25 in murine cancer cells result in inefficient adenovirus replication
When the adenoviral protein E1B55K binds death domain-associated protein (Daxx), the proteasome-dependent degradation of Daxx is initiated, and adenoviral replication is effectively maintained. Here, we show that the cellular levels of Daxx differ between human and mouse cancer cell lines. Specifica...
Kaydedildi:
| Yayımlandı: | Exp Mol Med |
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| Asıl Yazarlar: | , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group UK
2019
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6802665/ https://ncbi.nlm.nih.gov/pubmed/31615977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-019-0321-4 |
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