SPIN90, an adaptor protein, alters the proximity between Rab5 and Gapex5 and facilitates Rab5 activation during EGF endocytosis

During ligand-mediated receptor endocytosis, the small GTPase Rab5 functions in vesicle fusion and trafficking. Rab5 activation is known to require interactions with its guanine nucleotide-exchange factors (GEFs); however, the mechanism regulating Rab5 interactions with GEFs remains unclear. Here, w...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Exp Mol Med
Päätekijät: Kim, Hwan, Oh, Hyejin, Oh, Young Soo, Bae, Jeomil, Hong, Nan Hyung, Park, Su Jung, Ahn, Suyeon, Lee, Miriam, Rhee, Sangmyung, Lee, Sung Haeng, Jun, Youngsoo, Kim, Sung Hyun, Huh, Yun Hyun, Song, Woo Keun
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2019
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6802610/
https://ncbi.nlm.nih.gov/pubmed/31358736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-019-0284-5
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia