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Effect of EGF-receptor tyrosine kinase inhibitor on Rab5 function during endocytosis
Tyrosine autophosphorylation within the cytoplasmic tail of EGF-receptor is a key event, which in turn recruits several factors including Shc, Grb2 and Rin1 that are essential activities for receptor-mediated endocytosis and signaling. In this study, we demonstrated that treatment with AG1478, an EG...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3427926/ https://ncbi.nlm.nih.gov/pubmed/22683472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2012.05.023 |
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