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Epidermal Growth Factor and Membrane Trafficking: Egf Receptor Activation of Endocytosis Requires Rab5a

Activated epidermal growth factor receptors recruit various intracellular proteins leading to signal generation and endocytic trafficking. Although activated receptors are rapidly internalized into the endocytic compartment and subsequently degraded in lysosomes, the linkage between signaling and en...

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Detalhes bibliográficos
Main Authors: Barbieri, M. Alejandro, Roberts, Richard L., Gumusboga, Aysel, Highfield, Hilary, Alvarez-Dominguez, Carmen, Wells, Alan, Stahl, Philip D.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2185585/
https://ncbi.nlm.nih.gov/pubmed/11062256
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