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Gapex-5, a Rab31 Guanine Nucleotide Exchange Factor that Regulates Glut4 Trafficking in Adipocytes

Insulin stimulates glucose uptake by promoting translocation of the Glut4 glucose transporter from intracellular storage compartments to the plasma membrane. In the absence of insulin, Glut4 is retained intracellularly, although the mechanism underlying this process remains uncertain. Using the TC10...

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Autors principals: Lodhi, Irfan J., Chiang, Shian-Huey, Chang, Louise, Vollenweider, Daniel, Watson, Robert T., Inoue, Mayumi, Pessin, Jeffrey E., Saltiel, Alan R.
Format: Artigo
Idioma:Inglês
Publicat: 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779820/
https://ncbi.nlm.nih.gov/pubmed/17189207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2006.12.006
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