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Compartmentalization of the Exocyst Complex in Lipid Rafts Controls Glut4 Vesicle Tethering

Lipid raft microdomains act as organizing centers for signal transduction. We report here that the exocyst complex, consisting of Exo70, Sec6, and Sec8, regulates the compartmentalization of Glut4-containing vesicles at lipid raft domains in adipocytes. Exo70 is recruited by the G protein TC10 after...

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Detalhes bibliográficos
Main Authors: Inoue, Mayumi, Chiang, Shian-Huey, Chang, Louise, Chen, Xiao-Wei, Saltiel, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1446102/
https://ncbi.nlm.nih.gov/pubmed/16525015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-01-0030
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