Antitumor Activity of a Novel Tyrosine Kinase Inhibitor AIU2001 Due to Abrogation of the DNA Damage Repair in Non-Small Cell Lung Cancer Cells

Class III receptor tyrosine kinase (RTK) inhibitors targeting mainly FLT3 or c-KIT have not been well studied in lung cancer. To identify a small molecule potentially targeting class III RTK, we synthesized novel small molecule compounds and identified 5-(4-bromophenyl)-N-(naphthalen-1-yl) oxazol-2-...

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Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Ryu, Hwani, Choi, Hyun-Kyung, Kim, Hyo Jeong, Kim, Ah-Young, Song, Jie-Young, Hwang, Sang-Gu, Kim, Jae-Sung, Kim, Da-Un, Kim, Eun-Ho, Kim, Joon, Ahn, Jiyeon
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6801739/
https://ncbi.nlm.nih.gov/pubmed/31554189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20194728
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