Dynamic incorporation of histone H3 variants into chromatin is essential for acquisition of aggressive traits and metastatic colonization

Metastasis is the leading cause of cancer mortality. Chromatin remodeling provides the foundation for the cellular reprogramming necessary to drive metastasis. However, little is known about the nature of this remodeling and its regulation. Here, we show that metastasis-inducing pathways regulate hi...

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Publicat a:Cancer Cell
Autors principals: Gomes, Ana P., Ilter, Didem, Low, Vivien, Rosenzweig, Adam, Shen, Zih-Jie, Schild, Tanya, Rivas, Martin A., Er, Ekrem E., McNally, Dylan R., Mutvei, Anders P., Han, Julie, Ou, Yi-Hung, Cavaliere, Paola, Mullarky, Edouard, Nagiec, Michal, Shin, Sejeong, Yoon, Sang-Oh, Dephoure, Noah, Massagué, Joan, Melnick, Ari M., Cantley, Lewis C., Tyler, Jessica K., Blenis, John
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6801101/
https://ncbi.nlm.nih.gov/pubmed/31564638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2019.08.006
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