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Age-induced methylmalonic acid accumulation promotes tumor progression

From age 65 onwards, the risk of cancer incidence and associated mortality is substantially higher(1–6). Nonetheless, our understanding of the complex relationship between age and cancer is still in its infancy(2,3,7,8). For decades, this link has largely been attributed to increased exposure time t...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Gomes, Ana P., Ilter, Didem, Low, Vivien, Endress, Jennifer E., Fernández-García, Juan, Rosenzweig, Adam, Schild, Tanya, Broekaert, Dorien, Ahmed, Adnan, Planque, Melanie, Elia, Ilaria, Han, Julie, Kinzig, Charles, Mullarky, Edouard, Mutvei, Anders P., Asara, John, de Cabo, Rafael, Cantley, Lewis C., Dephoure, Noah, Fendt, Sarah-Maria, Blenis, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7785256/
https://ncbi.nlm.nih.gov/pubmed/32814897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2630-0
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