Dynamic incorporation of histone H3 variants into chromatin is essential for acquisition of aggressive traits and metastatic colonization

Metastasis is the leading cause of cancer mortality. Chromatin remodeling provides the foundation for the cellular reprogramming necessary to drive metastasis. However, little is known about the nature of this remodeling and its regulation. Here, we show that metastasis-inducing pathways regulate hi...

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Udgivet i:Cancer Cell
Main Authors: Gomes, Ana P., Ilter, Didem, Low, Vivien, Rosenzweig, Adam, Shen, Zih-Jie, Schild, Tanya, Rivas, Martin A., Er, Ekrem E., McNally, Dylan R., Mutvei, Anders P., Han, Julie, Ou, Yi-Hung, Cavaliere, Paola, Mullarky, Edouard, Nagiec, Michal, Shin, Sejeong, Yoon, Sang-Oh, Dephoure, Noah, Massagué, Joan, Melnick, Ari M., Cantley, Lewis C., Tyler, Jessica K., Blenis, John
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6801101/
https://ncbi.nlm.nih.gov/pubmed/31564638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2019.08.006
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