Dynamic incorporation of histone H3 variants into chromatin is essential for acquisition of aggressive traits and metastatic colonization

Metastasis is the leading cause of cancer mortality. Chromatin remodeling provides the foundation for the cellular reprogramming necessary to drive metastasis. However, little is known about the nature of this remodeling and its regulation. Here, we show that metastasis-inducing pathways regulate hi...

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Publicado no:Cancer Cell
Main Authors: Gomes, Ana P., Ilter, Didem, Low, Vivien, Rosenzweig, Adam, Shen, Zih-Jie, Schild, Tanya, Rivas, Martin A., Er, Ekrem E., McNally, Dylan R., Mutvei, Anders P., Han, Julie, Ou, Yi-Hung, Cavaliere, Paola, Mullarky, Edouard, Nagiec, Michal, Shin, Sejeong, Yoon, Sang-Oh, Dephoure, Noah, Massagué, Joan, Melnick, Ari M., Cantley, Lewis C., Tyler, Jessica K., Blenis, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6801101/
https://ncbi.nlm.nih.gov/pubmed/31564638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2019.08.006
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