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Steroyl-CoA Desaturase 1 (SCD1) protects ovarian cancer cells from ferroptotic cell death

Activation of ferroptosis, a recently described mechanism of regulated cell death, dramatically inhibits growth of ovarian cancer cells. Given the importance of lipid metabolism in ferroptosis and the key role of lipids in ovarian cancer, we examined the contribution to ferroptosis of steroyl CoA de...

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Détails bibliographiques
Publié dans:Cancer Res
Auteurs principaux: Tesfay, Lia, Paul, Bibbin T., Konstorum, Anna, Deng, Zhiyong, Cox, Anderson O., Lee, Jingyun, Furdui, Cristina M., Hegde, Poornima, Torti, Frank M., Torti, Suzy V.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6801059/
https://ncbi.nlm.nih.gov/pubmed/31270077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-0369
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