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Steroyl-CoA Desaturase 1 (SCD1) protects ovarian cancer cells from ferroptotic cell death

Activation of ferroptosis, a recently described mechanism of regulated cell death, dramatically inhibits growth of ovarian cancer cells. Given the importance of lipid metabolism in ferroptosis and the key role of lipids in ovarian cancer, we examined the contribution to ferroptosis of steroyl CoA de...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Tesfay, Lia, Paul, Bibbin T., Konstorum, Anna, Deng, Zhiyong, Cox, Anderson O., Lee, Jingyun, Furdui, Cristina M., Hegde, Poornima, Torti, Frank M., Torti, Suzy V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6801059/
https://ncbi.nlm.nih.gov/pubmed/31270077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-0369
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