Inhibition of Stearoyl-CoA Desaturase 1 (SCD1) Dissociates Insulin Resistance and Obesity From Atherosclerosis

BACKGROUND: Stearoyl-CoA Desaturase 1 (SCD1) is a well-known enhancer of the metabolic syndrome. The purpose of the present study was to investigate the role of SCD1 in lipoprotein metabolism and atherosclerosis progression. METHODS AND RESULTS: Antisense oligonucleotides were used to inhibit SCD1 i...

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Main Authors: Brown, J. Mark, Chung, Soonkyu, Sawyer, Janet K., Degirolamo, Chiara, Alger, Heather M., Nguyen, Tam, Zhu, Xuewei, Duong, My-Ngan, Wibley, Amanda L., Shah, Ramesh, Davis, Matthew A., Kelley, Kathryn, Wilson, Martha D., Kent, Carol, Parks, John S., Rudel, Lawrence L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716169/
https://ncbi.nlm.nih.gov/pubmed/18794388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.108.793182
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