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Withaferin A inhibits expression of ataxia telangiectasia and Rad3-related kinase and enhances sensitivity of human breast cancer cells to cisplatin
Ataxia telangiectasia and Rad3-related (ATR) is a serine/threonine-specific kinase that plays an important role in the maintenance of genomic integrity. In this study, we investigated the role of ATR in cell cycle arrest by withaferin A (WA), a cancer preventative steroidal lactone derived from With...
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| Publicado en: | Mol Carcinog |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6800812/ https://ncbi.nlm.nih.gov/pubmed/31441116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.23104 |
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