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Withaferin A Suppresses Estrogen Receptor-α Expression in Human Breast Cancer Cells

We have shown previously that withaferin A (WA), a promising anticancer constituent of Ayurvedic medicine plant Withania somnifera, inhibits growth of MCF-7 and MDA-MB-231 human breast cancer cells in culture and MDA-MB-231 xenografts in vivo by causing apoptosis. However, the mechanism of WA-induce...

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Detalhes bibliográficos
Main Authors: Hahm, Eun-Ryeong, Lee, Joomin, Huang, Yi, Singh, Shivendra V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129407/
https://ncbi.nlm.nih.gov/pubmed/21432907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.20760
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