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Role of Mitogen-Activated Protein Kinases and Mcl-1 in Apoptosis Induction by Withaferin A in Human Breast Cancer Cells

Withaferin A (WA), a bioactive constituent of Ayurvedic medicine plant Withania somnifera, is a potent apoptosis inducer in cancer cells but the mechanism of cell death induction is not fully characterized. The present study was undertaken to determine the role of mitogen-activated protein kinases (...

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Autors principals: Hahm, Eun-Ryeong, Lee, Joomin, Singh, Shivendra V.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859703/
https://ncbi.nlm.nih.gov/pubmed/24019090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22050
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