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Early Postnatal Exposure to Isoflurane Disrupts Oligodendrocyte Development and Myelin Formation in the Mouse Hippocampus.
BACKGROUND: Early postnatal exposure to general anesthetics may interfere with brain development. We tested the hypothesis that isoflurane causes a lasting disruption in myelin development via actions on the mammalian target of rapamycin (mTOR) pathway. METHODS: Mice were exposed to 1.5% isoflurane...
Tallennettuna:
| Julkaisussa: | Anesthesiology |
|---|---|
| Päätekijät: | , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2019
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6800770/ https://ncbi.nlm.nih.gov/pubmed/31436548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000002904 |
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