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Aspartoacylase deficiency affects early postnatal development of oligodendrocytes and myelination
Canavan disease (CD) is a neurodegenerative disease, caused by a deficiency in the enzyme aspartoacylase (ASPA). This enzyme has been localized to oligodendrocytes; however, it is still undefined how ASPA deficiency affects oligodendrocyte development. In normal mice the pattern of ASPA expression c...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2964840/ https://ncbi.nlm.nih.gov/pubmed/20637282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2010.07.003 |
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