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DOT1L complex suppresses transcription from enhancer elements and ectopic RNAi in Caenorhabditis elegans
Methylation of histone H3 on lysine 79 (H3K79) by DOT1L is associated with actively transcribed genes. Earlier, we described that DOT-1.1, the Caenorhabditis elegans homolog of mammalian DOT1L, cooperates with the chromatin-binding protein ZFP-1 (AF10 homolog) to negatively modulate transcription of...
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| Publié dans: | RNA |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cold Spring Harbor Laboratory Press
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6800474/ https://ncbi.nlm.nih.gov/pubmed/31300558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.070292.119 |
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