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Transcriptional silencing of a transgene by RNAi in the soma of C. elegans

The silencing of transgene expression at the level of transcription in the soma of Caenorhabditis elegans through an RNAi-dependent pathway has not been previously characterized. Most gene silencing due to RNAi in C. elegans occurs at the post-transcriptional level. We observed transcriptional silen...

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Detalhes bibliográficos
Main Authors: Grishok, Alla, Sinskey, Jina L., Sharp, Phillip A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1065722/
https://ncbi.nlm.nih.gov/pubmed/15741313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1247705
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