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CSR-1 RNAi pathway positively regulates histone expression in C. elegans
Endogenous small interfering RNAs (endo-siRNAs) have been discovered in many organisms, including mammals. In C. elegans, depletion of germline-enriched endo-siRNAs found in complex with the CSR-1 Argonaute protein causes sterility and defects in chromosome segregation in early embryos. We discovere...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2012
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3463841/ https://ncbi.nlm.nih.gov/pubmed/22863779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.216 |
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