DOT1L complex suppresses transcription from enhancer elements and ectopic RNAi in Caenorhabditis elegans

Methylation of histone H3 on lysine 79 (H3K79) by DOT1L is associated with actively transcribed genes. Earlier, we described that DOT-1.1, the Caenorhabditis elegans homolog of mammalian DOT1L, cooperates with the chromatin-binding protein ZFP-1 (AF10 homolog) to negatively modulate transcription of...

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Bibliografiske detaljer
Udgivet i:RNA
Main Authors: Esse, Ruben, Gushchanskaia, Ekaterina S., Lord, Avery, Grishok, Alla
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2019
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Bioinformatics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800474/
https://ncbi.nlm.nih.gov/pubmed/31300558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.070292.119
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