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Specificity, versatility and control of TGF-β family signaling

Encoded in mammalian cells by 33 genes, the transforming growth factor-β (TGF-β) family of secreted, homodimeric and heterodimeric proteins controls cell differentiation of most, if not all, lineages and many aspects of cell and tissue physiology in multicellular eukaryotes. Deregulation of TGF-β fa...

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Bibliographic Details
Published in:Sci Signal
Main Authors: Derynck, Rik, Budi, Erine H.
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800142/
https://ncbi.nlm.nih.gov/pubmed/30808818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aav5183
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