2349 The role of interleukin-23 in human melanoma

OBJECTIVES/SPECIFIC AIMS: Interleukin-23 (IL-23) promotes differentiation of naïve T-cells into Th17 cells, which drive the pathogenesis of autoinflammatory conditions such as psoriasis. IL-23-neutralizing antibody therapies are now in use for treatment of psoriasis, with promising results. Studies...

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Dettagli Bibliografici
Pubblicato in:J Clin Transl Sci
Autori principali: Jani, Aditi, Chaudhary, Sandeep, Janjetovic, Zorica, Sherwani, Mohammad A., Yusuf, Nabiha, Slominski, Andrzej, Athar, Mohammad, Elmets, Craig
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cambridge University Press 2018
Soggetti:
Basic/Translational Science/Team Science
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798532/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2018.135
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