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Inhibition of interleukin‐12 and/or interleukin‐23 for the treatment of psoriasis: What is the evidence for an effect on malignancy?

Immune cells and cytokines play an important role in the pathogenesis of psoriasis. Interleukin‐12 (IL‐12) and IL‐23 promote cellular responses mediated by T cells, which contribute to an inflammatory loop responsible for the induction and maintenance of psoriatic plaques. Antibodies that inhibit IL...

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Библиографические подробности
Опубликовано в: :Exp Dermatol
Главные авторы: Ergen, Elizabeth N., Yusuf, Nabiha
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6023723/
https://ncbi.nlm.nih.gov/pubmed/29704872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/exd.13676
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