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Inhibition of interleukin‐12 and/or interleukin‐23 for the treatment of psoriasis: What is the evidence for an effect on malignancy?

Immune cells and cytokines play an important role in the pathogenesis of psoriasis. Interleukin‐12 (IL‐12) and IL‐23 promote cellular responses mediated by T cells, which contribute to an inflammatory loop responsible for the induction and maintenance of psoriatic plaques. Antibodies that inhibit IL...

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Detalhes bibliográficos
Publicado no:Exp Dermatol
Main Authors: Ergen, Elizabeth N., Yusuf, Nabiha
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6023723/
https://ncbi.nlm.nih.gov/pubmed/29704872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/exd.13676
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