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20,23-Dihydroxyvitamin D3, Novel P450scc Product, Stimulates Differentiation and Inhibits Proliferation and NF-κB Activity in Human Keratinocytes

We have examined effects of the 20,23-dihydroxyvitamin D3 (20,23(OH)2D3), on differentiation and proliferation of human keratinocytes and the anti-inflammatory potential of 20,23(OH)2D3 from its action on nuclear factor-κB (NF-κB). 20,23(OH)2D3 inhibited growth of keratinocytes with a potency compar...

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Detalhes bibliográficos
Main Authors: JANJETOVIC, ZORICA, TUCKEY, ROBERT C., NGUYEN, MINH N., THORPE, EDWIN M., SLOMINSKI, ANDRZEJ T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814891/
https://ncbi.nlm.nih.gov/pubmed/20020487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21992
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