Cytochrome P450scc-dependent metabolism of 7-dehydrocholesterol in placenta and epidermal keratinocytes

The discovery that 7-dehydrocholesterol (7DHC) is an excellent substrate for cytochrome P450scc (CYP11A1) opens up new possibilities in biochemistry. To elucidate its biological significance we tested ex-vivo P450scc-dependent metabolism of 7DHC by tissues expressing high and low levels of P450scc a...

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Detalhes bibliográficos
Main Authors: Slominski, Andrzej T., Kim, Tae-Kang, Chen, Jianjun, Nguyen, Minh N., Li, Wei, Yates, Charles R., Sweatman, Trevor, Janjetovic, Zorica, Tuckey, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3520099/
https://ncbi.nlm.nih.gov/pubmed/22877869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2012.07.027
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