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Metabolism of 1α-hydroxyvitamin D3 by cytochrome P450scc to biologically active 1α,20-dihydroxyvitamin D3

Cytochrome P450scc (CYP11A1) metabolizes vitamin D3 to 20-hydroxyvitamin D3 as the major product, with subsequent production of dihydroxy and trihydroxy derivatives. The aim of this study was to determine whether cytochrome P450scc could metabolize 1α-hydroxyvitamin D3 and whether products were biol...

詳細記述

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書誌詳細
主要な著者: Tuckey, Robert C., Janjetovic, Zorica, Li, Wei, Nguyen, Minh N., Zmijewski, Michal A., Zjawiony, Jordan, Slominski, Andrzej
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605774/
https://ncbi.nlm.nih.gov/pubmed/19000766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2008.10.005
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