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KRAS and BRAF mutations induce anoikis resistance and characteristic 3D phenotypes in Caco-2 cells
In a number of types of cancer, anoikis, a form of apoptosis induced by loss of extracellular matrix (ECM) attachment, is disturbed. Anoikis resistance is essential in the formation of metastases. A recent study identified carcinoma cell subpopulations surviving without ECM contact in pathological s...
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| Veröffentlicht in: | Mol Med Rep |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
D.A. Spandidos
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6797985/ https://ncbi.nlm.nih.gov/pubmed/31545494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2019.10693 |
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