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KRAS and BRAF mutations induce anoikis resistance and characteristic 3D phenotypes in Caco-2 cells

In a number of types of cancer, anoikis, a form of apoptosis induced by loss of extracellular matrix (ECM) attachment, is disturbed. Anoikis resistance is essential in the formation of metastases. A recent study identified carcinoma cell subpopulations surviving without ECM contact in pathological s...

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Bibliografische gegevens
Gepubliceerd in:Mol Med Rep
Hoofdauteurs: Patankar, Madhura, Eskelinen, Sinikka, Tuomisto, Anne, Mäkinen, Markus J., Karttunen, Tuomo J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: D.A. Spandidos 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6797985/
https://ncbi.nlm.nih.gov/pubmed/31545494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2019.10693
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