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Advances in gene therapy for cystic fibrosis lung disease

Cystic fibrosis (CF) is a multiorgan recessive genetic disease caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Gene therapy efforts have focused on treating the lung, since it manifests the most significant life-threatening disease. Over two decades have p...

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書目詳細資料
發表在:Hum Mol Genet
Main Authors: Yan, Ziying, McCray Jr, Paul B, Engelhardt, John F
格式: Artigo
語言:Inglês
出版: Oxford University Press 2019
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796993/
https://ncbi.nlm.nih.gov/pubmed/31332440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddz139
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