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Ferret and Pig Models of Cystic Fibrosis: Prospects and Promise for Gene Therapy

Large animal models of genetic diseases are rapidly becoming integral to biomedical research as technologies to manipulate the mammalian genome improve. The creation of cystic fibrosis (CF) ferrets and pigs is an example of such progress in animal modeling, with the disease phenotypes in the ferret...

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Bibliografiske detaljer
Udgivet i:Hum Gene Ther Clin Dev
Main Authors: Yan, Ziying, Stewart, Zoe A., Sinn, Patrick L., Olsen, John C., Hu, Jim, McCray, Paul B., Engelhardt, John F.
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367511/
https://ncbi.nlm.nih.gov/pubmed/25675143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/humc.2014.154
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