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Ferret and Pig Models of Cystic Fibrosis: Prospects and Promise for Gene Therapy

Large animal models of genetic diseases are rapidly becoming integral to biomedical research as technologies to manipulate the mammalian genome improve. The creation of cystic fibrosis (CF) ferrets and pigs is an example of such progress in animal modeling, with the disease phenotypes in the ferret...

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Detalles Bibliográficos
Publicado en:Hum Gene Ther Clin Dev
Autores principales: Yan, Ziying, Stewart, Zoe A., Sinn, Patrick L., Olsen, John C., Hu, Jim, McCray, Paul B., Engelhardt, John F.
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367511/
https://ncbi.nlm.nih.gov/pubmed/25675143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/humc.2014.154
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