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Ferret and Pig Models of Cystic Fibrosis: Prospects and Promise for Gene Therapy

Large animal models of genetic diseases are rapidly becoming integral to biomedical research as technologies to manipulate the mammalian genome improve. The creation of cystic fibrosis (CF) ferrets and pigs is an example of such progress in animal modeling, with the disease phenotypes in the ferret...

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Detalhes bibliográficos
Publicado no:Hum Gene Ther Clin Dev
Main Authors: Yan, Ziying, Stewart, Zoe A., Sinn, Patrick L., Olsen, John C., Hu, Jim, McCray, Paul B., Engelhardt, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367511/
https://ncbi.nlm.nih.gov/pubmed/25675143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/humc.2014.154
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