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Advances in Cell and Gene-based Therapies for Cystic Fibrosis Lung Disease

Cystic fibrosis (CF) is a disease characterized by airway infection, inflammation, remodeling, and obstruction that gradually destroy the lungs. Direct delivery of the cystic fibrosis transmembrane conductance regulator (CFTR) gene to airway epithelia may offer advantages, as the tissue is accessibl...

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Detalhes bibliográficos
Main Authors: Oakland, Mayumi, Sinn, Patrick L, McCray Jr, Paul B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369283/
https://ncbi.nlm.nih.gov/pubmed/22371844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.32
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