BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules

Error-free mitosis depends on accurate chromosome attachment to spindle microtubules, powered congression of those chromosomes, their segregation in anaphase, and assembly of a spindle midzone at mitotic exit. The centromere-associated kinesin motor CENP-E, whose binding partner is BubR1, has been i...

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Publicat a:Cell Res
Autors principals: Huang, Yuejia, Lin, Lin, Liu, Xing, Ye, Sheng, Yao, Phil Y., Wang, Wenwen, Yang, Fengrui, Gao, Xinjiao, Li, Junying, Zhang, Yin, Zhang, Jiancun, Yang, Zhihong, Liu, Xu, Yang, Zhenye, Zang, Jianye, Teng, Maikun, Wang, Zhiyong, Ruan, Ke, Ding, Xia, Li, Lin, Cleveland, Don W., Zhang, Rongguang, Yao, Xuebiao
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796941/
https://ncbi.nlm.nih.gov/pubmed/31201382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-019-0178-z
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