Wird geladen...
NDP52 tunes cortical actin interaction with astral microtubules for accurate spindle orientation
Oriented cell divisions are controlled by a conserved molecular cascade involving Gαi, LGN, and NuMA. Here, we show that NDP52 regulates spindle orientation via remodeling the polar cortical actin cytoskeleton. siRNA-mediated NDP52 suppression surprisingly revealed a ring-like compact subcortical F-...
Gespeichert in:
| Veröffentlicht in: | Cell Res |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2019
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6796859/ https://ncbi.nlm.nih.gov/pubmed/31201383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-019-0189-9 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|