NDP52 tunes cortical actin interaction with astral microtubules for accurate spindle orientation

Oriented cell divisions are controlled by a conserved molecular cascade involving Gαi, LGN, and NuMA. Here, we show that NDP52 regulates spindle orientation via remodeling the polar cortical actin cytoskeleton. siRNA-mediated NDP52 suppression surprisingly revealed a ring-like compact subcortical F-...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Res
Main Authors: Yu, Huijuan, Yang, Fengrui, Dong, Peng, Liao, Shanhui, Liu, Wei R., Zhao, Gangyin, Qin, Bo, Dou, Zhen, Liu, Zhe, Liu, Wei, Zang, Jianye, Lippincott-Schwartz, Jennifer, Liu, Xing, Yao, Xuebiao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796859/
https://ncbi.nlm.nih.gov/pubmed/31201383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-019-0189-9
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados