ASPM and CITK regulate spindle orientation by affecting the dynamics of astral microtubules

Correct orientation of cell division is considered an important factor for the achievement of normal brain size, as mutations in genes that affect this process are among the leading causes of microcephaly. Abnormal spindle orientation is associated with reduction of the neuronal progenitor symmetric...

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Veröffentlicht in:EMBO Rep
Hauptverfasser: Gai, Marta, Bianchi, Federico T, Vagnoni, Cristiana, Vernì, Fiammetta, Bonaccorsi, Silvia, Pasquero, Selina, Berto, Gaia E, Sgrò, Francesco, Chiotto, Alessandra MA, Annaratone, Laura, Sapino, Anna, Bergo, Anna, Landsberger, Nicoletta, Bond, Jacqueline, Huttner, Wieland B, Di Cunto, Ferdinando
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2016
Schlagworte:
Scientific Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048379/
https://ncbi.nlm.nih.gov/pubmed/27562601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201541823
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