ASPM and CITK regulate spindle orientation by affecting the dynamics of astral microtubules

Correct orientation of cell division is considered an important factor for the achievement of normal brain size, as mutations in genes that affect this process are among the leading causes of microcephaly. Abnormal spindle orientation is associated with reduction of the neuronal progenitor symmetric...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Gai, Marta, Bianchi, Federico T, Vagnoni, Cristiana, Vernì, Fiammetta, Bonaccorsi, Silvia, Pasquero, Selina, Berto, Gaia E, Sgrò, Francesco, Chiotto, Alessandra MA, Annaratone, Laura, Sapino, Anna, Bergo, Anna, Landsberger, Nicoletta, Bond, Jacqueline, Huttner, Wieland B, Di Cunto, Ferdinando
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Scientific Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048379/
https://ncbi.nlm.nih.gov/pubmed/27562601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201541823
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