NANOG helps cancer cells escape NK cell attack by downregulating ICAM1 during tumorigenesis

BACKGROUND: At the beginning of tumorigenesis, newly born cancer cells must successfully avoid attack by the immune system. Although most abnormal cells are efficiently identified and destroyed by the immune system, particularly by NK cells, the molecular mechanisms by which newly born cancer cells...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:J Exp Clin Cancer Res
Autori principali: Saga, Kotaro, Park, Jinhee, Nimura, Keisuke, Kawamura, Norihiko, Ishibashi, Airi, Nonomura, Norio, Kaneda, Yasufumi
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796413/
https://ncbi.nlm.nih.gov/pubmed/31619256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1429-z
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