NANOG helps cancer cells escape NK cell attack by downregulating ICAM1 during tumorigenesis

BACKGROUND: At the beginning of tumorigenesis, newly born cancer cells must successfully avoid attack by the immune system. Although most abnormal cells are efficiently identified and destroyed by the immune system, particularly by NK cells, the molecular mechanisms by which newly born cancer cells...

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Publicat a:J Exp Clin Cancer Res
Autors principals: Saga, Kotaro, Park, Jinhee, Nimura, Keisuke, Kawamura, Norihiko, Ishibashi, Airi, Nonomura, Norio, Kaneda, Yasufumi
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796413/
https://ncbi.nlm.nih.gov/pubmed/31619256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1429-z
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