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NANOG helps cancer cells escape NK cell attack by downregulating ICAM1 during tumorigenesis

BACKGROUND: At the beginning of tumorigenesis, newly born cancer cells must successfully avoid attack by the immune system. Although most abnormal cells are efficiently identified and destroyed by the immune system, particularly by NK cells, the molecular mechanisms by which newly born cancer cells...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Saga, Kotaro, Park, Jinhee, Nimura, Keisuke, Kawamura, Norihiko, Ishibashi, Airi, Nonomura, Norio, Kaneda, Yasufumi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796413/
https://ncbi.nlm.nih.gov/pubmed/31619256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1429-z
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